Both the Telluride and Ascent have child safety locks to prevent children from opening the rear doors. The Telluride has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Ascent’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Telluride has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The Ascent doesn’t offer front seat center airbags.
Both the Telluride and Ascent have rear cross-traffic warning, but the Telluride has Rear Cross-Traffic Collision-Avoidance Assist (automatically applies the brakes) to better prevent a collision when backing near traffic. The Ascent’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the Telluride and the Ascent have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, available all wheel drive and around view monitors.

